Priv.-Doz. Dr. med. Bernhard Kreymann, nephrologist and founder of ADVITOS GmbH (previously Hepa Wash GmbH), has been working on the topic of liver and multi-organ support since 1994. During his time at the Munich University Hospital Rechts der Isar, he invented single-pass albumin dialysis in 1995, which is still used today to stabilize patients until liver transplantation. However, the method is not effective or inexpensive enough to be used more widely in everyday clinical practice.

Due to the high financial requirements, further development of a single pass albumin dialysis could not be done at the university. As a result, Hepa Wash was founded as a one-man start-up in a research lab in Garching near Munich in mid-2005. The development of the company was made possible over the years by means of several financing rounds by private investors, KfW banking groups and employees. The idea was to implement effective liver support therapy from concept to marketing. Not only has that goal been achieved, but today’s ADVOS procedure is suitable both for hepatic dialysis and is the first method in the world for extended and individualized support of the main detoxification organs: the liver, lungs and kidneys.

  • The versatility and complexity of the human organism regularly presents medicine with therapeutic challenges for reliable treatment options for patients in intensive care all over the world.

    We are looking for reliable treatment methods to close the therapeutic gap in multi-organ failure.

  • Since its founding in 2005, ADVITOS GmbH has devoted itself to the development of effective multi-organ support.

    We are developing novel medical products with a focus on patient safety and user-friendliness.

  • The most advanced medical and engineering art in a safe, functional and user-friendly product, the ADVOS multi has achieved the originally set goal after numerous in-vitro tests, pre-clinical and clinical studies: the ADVOS procedure was approved in Europe and clinical users have given it a clear and positive response.

    Leading university clinics nationwide work with the promising approach of the ADVOS procedure.